Historic buildings dating from the 1850s to the 1950s are found throughout Muscatine. These buildings provide a glimpse into times of the past and reflect the history of the community through the built environment. 

Identification and evaluation of the historic buildings in Muscatine is one of the primary goals of the Muscatine Historic Preservation Commission. The Muscatine Historic Preservation Commission was formed by local ordinance in 2000, consisting of five members. They hold regular monthly meetings that are open to the public.